PT-141

Q: What is the difference between PT-141 and Melanotan II?

PT-141 is derived from Melanotan II but lacks the acetyl group and carboxamide modification. PT-141 is more selective for CNS melanocortin pathways and does not produce the same degree of skin pigmentation in research models.

Q: Which melanocortin receptors does PT-141 target?

PT-141 primarily targets MC3R and MC4R receptors, which are expressed in the hypothalamus and other CNS regions involved in autonomic regulation.

PT-141

PT-141 (Bremelanotide)

Research Use Only · Not for Human Consumption

PT-141 (Bremelanotide) is a cyclic heptapeptide and a melanocortin receptor agonist, specifically targeting MC3R and MC4R receptors in the central nervous system. It is derived from the alpha-MSH (alpha-melanocyte-stimulating hormone) peptide family and was developed from Melanotan II research. PT-141 is distinct from other peptides in the catalog because its primary research focus is on central nervous system pathways rather than peripheral tissue effects.

Key Facts

Amino acid count: 7 (cyclic)
Receptors: MC3R and MC4R
Type: Melanocortin receptor agonist
Storage: -20°C lyophilized

Research Applications

CNS-mediated arousal pathway research
Melanocortin receptor signaling studies
Hypothalamic regulation research
Alpha-MSH analog studies

Frequently Asked Questions

What is the difference between PT-141 and Melanotan II?

Which melanocortin receptors does PT-141 target?

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Key Facts

Research Applications

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