Lipolysis
Lipolysis (Fat Breakdown)
Research Use Only · Not for Human Consumption
Lipolysis is the metabolic process of hydrolytic cleavage of triglycerides (stored fats) in adipocytes into glycerol and free fatty acids (FFAs). These FFAs enter the bloodstream and are used as fuel by peripheral tissues. Lipolysis is regulated by hormones including catecholamines (which stimulate it via beta-adrenergic receptors) and insulin (which suppresses it). Research peptides such as AOD-9604 and semaglutide are studied for their effects on lipolytic pathways.
Key Facts
- Substrate
- Triglycerides (triacylglycerols)
- Products
- Glycerol + free fatty acids
- Stimulated by
- Catecholamines, glucagon
- Inhibited by
- Insulin
- Key enzyme
- Hormone-sensitive lipase (HSL)
Research Applications
- Metabolic research in adipose tissue
- Obesity and body composition research
- Beta-adrenergic receptor pharmacology
- Peptide effects on fat metabolism studies
Frequently Asked Questions
Related Terms
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