AOD-9604

Q: Does AOD-9604 act like growth hormone?

No. AOD-9604 does not bind the GH receptor and does not produce IGF-1 elevation. Its lipolytic effects operate through a separate mechanism involving beta-3 adrenergic pathways.

Q: Why is AOD-9604 of interest in metabolic research?

Its direct lipolytic activity without GH receptor signaling makes it a useful research tool for isolating the fat-metabolism aspects of the GH molecule from its growth-promoting effects.

AOD-9604

Anti-Obesity Drug 9604

Research Use Only · Not for Human Consumption

AOD-9604 is a modified fragment of human growth hormone (hGH), specifically the C-terminal peptide of hGH spanning residues 176–191, with a tyrosine added at the N-terminus. Unlike hGH, AOD-9604 does not bind the GH receptor or produce IGF-1-related effects. Research has focused on its direct lipolytic properties via beta-3 adrenergic receptor stimulation and adipogenesis inhibition.

Key Facts

Based on: hGH fragment 176–191
Type: hGH C-terminal analog
GH receptor binding: None
Storage: -20°C lyophilized

Research Applications

Lipolysis mechanism research
Adipogenesis inhibition studies
Beta-3 adrenergic receptor research
Body composition research models

Frequently Asked Questions

Does AOD-9604 act like growth hormone?

Why is AOD-9604 of interest in metabolic research?

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Key Facts

Research Applications

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