Peptide
IGF-1 LR3
Insulin-like Growth Factor 1 Long Arg3
Research Use Only · Not for Human Consumption
IGF-1 LR3 (Long Arg3 IGF-1) is a synthetic analog of insulin-like growth factor 1 (IGF-1) with an Arg3 substitution and a 13-amino-acid N-terminal extension. These modifications reduce its affinity for IGF-binding proteins (IGFBPs), extend its half-life from approximately 12 hours (native IGF-1) to about 20–30 hours, and lower its insulin receptor affinity. IGF-1 LR3 is a standard research tool for IGF-1 receptor pathway studies.
Key Facts
- Modification
- Long R3 extension + Arg3 substitution
- Half-life vs native IGF-1
- ~20–30 hrs vs ~12 hrs
- IGFBP binding
- Reduced
- Storage
- -20°C lyophilized
Research Applications
- IGF-1 receptor signaling studies
- Muscle satellite cell proliferation research
- Myoblast differentiation studies
- GH/IGF-1 axis modeling
- Protein synthesis pathway research
Frequently Asked Questions
Related Terms
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