Peptide

Sermorelin

Q: Is sermorelin a natural peptide?

Sermorelin is synthetic but based on a naturally occurring sequence — the first 29 amino acids of human GHRH. It retains the receptor-binding activity of the full native peptide.

Q: How does sermorelin compare to CJC-1295?

Both are GHRH analogs. Sermorelin has a shorter half-life and represents the naturally occurring 1-29 fragment. CJC-1295 has modifications that extend its half-life significantly.

Sermorelin (GHRH 1-29)

Research Use Only · Not for Human Consumption

Sermorelin is a synthetic peptide consisting of the first 29 amino acids (1-29) of the 44-amino-acid endogenous growth hormone-releasing hormone (GHRH). This N-terminal fragment retains full biological activity at the GHRH receptor. Sermorelin was one of the first GHRH analogs developed for research and has a well-established preclinical safety profile.

Key Facts

Amino acid count: 29
Type: GHRH 1-29 analog
Receptor: GHRH receptor (GHRHR)
Storage: -20°C lyophilized

Research Applications

Pituitary GHRH receptor signaling
GH axis evaluation models
Somatotroph function studies
Pediatric growth hormone studies

Frequently Asked Questions

Is sermorelin a natural peptide?

How does sermorelin compare to CJC-1295?

Related Terms

CJC-1295 Ipamorelin Tesamorelin GHRP-2

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