HPLC (High-Performance Liquid Chromatography) is an analytical chemistry technique used to separate, identify, and quantify compounds in a mixture. In peptide testing, it determines purity by measuring the percentage of the target peptide versus impurities.

COA — Research Peptide Definition

Q: What does a COA confirm?

A COA confirms the molecular identity (via mass spec), purity percentage (via HPLC), and batch number of a compound. It verifies the product matches its label claims.

Q: Why do research compound retailers provide COAs?

COAs are the primary quality assurance mechanism in the research peptide industry. Retailers that provide third-party COAs for every batch demonstrate product authenticity and quality to their customers.

COA

Certificate of Analysis

Research Use Only · Not for Human Consumption

A Certificate of Analysis (COA) is an analytical document issued by a qualified testing laboratory that confirms the identity, purity, and quantity of a compound in a given batch. For research peptides, COAs typically include mass spectrometry (MS) and/or HPLC results confirming molecular weight identity and purity percentage. COAs from third-party (independent) labs are considered the gold standard in the research compound industry.

Key Facts

Issued by: Third-party testing laboratory
Key tests: Mass spectrometry, HPLC
Confirms: Identity, purity percentage, batch number
Standard purity: ≥98% for research-grade peptides

Research Applications

Quality verification for research compounds
Batch-level documentation for compliance
Buyer due diligence in compound procurement
Regulatory documentation for research institutions

Frequently Asked Questions

What does a COA confirm?

What is HPLC?

Why do research compound retailers provide COAs?

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COA

Key Facts

Research Applications

Frequently Asked Questions

Related Terms

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